Evolutionary and functional analysis of DNA methyltransferases in micro-eukaryotes: Insights from the model diatom Phaeodactylum tricornutum [Bisulfite-Seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE186855
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资源简介:
DNA methylation has been associated with transcriptional repression of transposable elements. Here we describe the first DNA methylation deficient cell line of a diatom by generating DNMT5:KOs in Phaeodactylum tricornutum. These data show the extend of the loss of DNA methylation in DNMT5:KOs compared to the reference strain. All DNA methylation is lost in DNMT5:KOs. 3 conditions - 2 independent DNMT5:KOs -> DNMT5:KO line M23 ; DNMT5:KO line M25 + 1 reference strain "WT" Pt18.6. 1 replicate per condition.
创建时间:
2023-03-17



