A distinct T cell receptor signature associates with cardiac outcome in myocardial infarction patients

A distinct T cell receptor signature associates with cardiac outcome in myocardial infarction patients. This folder contains the dataset, metadata and annotated files supporting the results. Raw fastq files can be found at PRJNA1452490. Structure : aligned: contained MIXCR v3.12 aligned files. code : - analysis : R scripts used to produce the figures - model_pgen_pdata: Scripts used to compute the signature using pgen/pdata synthetic_repertoire : synthetic repertoires used to compute the Pgen/Pdata tables : relevant tables for the analysis metadata.csv : sample information table for clonotype analysis clonotype_table.rds : complete clonotype tables from aligned data 348_mi_signature.csv : final signature with corresponding pgen/pdata/pvalues vj_usage.rds : RDS object containing TR gene usage in dataset table_clinical_data.xlsx : clinical table used in the figures Clinical parameters summarized.docx : summary of clinical parameters