RNA-sequencing technology identifies specific genes expressed in the ICM of mouse embryos

RNA-seq data from whole mouse embryos at E3.75 (stage where the three cell types: TE, PrE and EPI are well resolved) and from dissected ICMs in order to identify genes expressed specifically in the ICM We used E3.75 whole mouse embryos at the blastocyst stage and immunosurgically dissected ICMs for RNA extraction and sequencing本数据集涵盖小鼠胚胎发育第3.75天（E3.75）的全胚胎RNA测序（RNA-seq）数据——该阶段滋养外胚层（Trophectoderm, TE）、原始内胚层（Primitive Endoderm, PrE）与上胚层（Epiblast, EPI）三种细胞类型已清晰分辨——以及经解剖获取的内细胞团（Inner Cell Mass, ICM）的RNA-seq数据，用于鉴定特异性表达于内细胞团的基因。本研究采用囊胚期E3.75小鼠全胚胎与免疫外科剥离的内细胞团进行RNA提取及测序。