BP Figure-2: Effects of a high-fat diet on blood lipids and liver GK activity.

P446L mice of the PP or PL genotypes (n=7,7) were fed on either regular diet (RD, open bar) or the high-fat diet (HFD, hashed) for 2 wk. A) Increase in epididymal fat pad mass on the HFD. B) Increase in blood triglyceride and cholesterol and increase in liver GK activity in PL mice on the HFD. *P < 0.05 effect of diet; #P < 0.05 effect of genotype.

对PP或PL基因型（n=7,7）的P446L小鼠分别喂养标准饮食（RD，开放式饮食）或高脂肪饮食（HFD，粉碎饮食）持续2周。A）在高脂肪饮食下，附睾脂肪垫质量的增加。B）PL小鼠在高脂肪饮食下血液甘油三酯和胆固醇水平的升高，以及肝脏GK活性的增加。*P < 0.05表示饮食的影响；#P < 0.05表示基因型的影响。