Crystal structure of human PI3K-gamma in complex with benzimidazole inhibitor 5
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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Crystal structure of human PI3K-gamma in complex with benzimidazole inhibitor 5 Descriptor: 4-azanyl-6-[[(1~{S})-1-[6-fluoranyl-1-(3-methylsulfonylphenyl)benzimidazol-2-yl]ethyl]amino]pyrimidine-5-carbonitrile, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION Authors: Whittington, D.A, Tang, J, Yakowec, P. Deposit date: 2015-10-21 Release date: 2015-12-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3K delta Inhibitors. J.Med.Chem., 59, 2016
创建时间：
2015-10-21
