five

Raw data supporting all figures in the manuscript

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NIAID Data Ecosystem2026-05-10 收录
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https://figshare.com/articles/dataset/Raw_data_supporting_all_figures_in_the_manuscript/31980369
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This study investigated whether exosomes derived from PTX-resistant breast cancer cells induce chemoresistance in parental cells via the p53/PI3K/AKT/mTOR pathway. Exosomes from PTX-sensitive and PTX-resistant cells (MCF-7 and MDA-MB-231) were isolated and characterized, and functional assays (CCK-8, TUNEL, qRT-PCR, and Western blotting), along with bioinformatics analysis, miRNA inhibition, and p53 overexpression, were performed for mechanistic validation.
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2026-04-10
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