OXA-48_Q5-CAZ. Epistasis Arises from Shifting the Rate-Limiting Step during Enzyme Evolution
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OXA-48_Q5-CAZ. Epistasis Arises from Shifting the Rate-Limiting Step during Enzyme Evolution Descriptor: 1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-oxoethyl]-4-carboxy-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium, Beta-lactamase, CHLORIDE ION Authors: Leiros, H.-K.S, Frohlich, C. Deposit date: 2023-06-13 Release date: 2024-02-14 Last modified: 2025-10-01 Method: X-RAY DIFFRACTION (2.66 Å) Cite: Epistasis arises from shifting the rate-limiting step during enzyme evolution of a beta-lactamase. Nat Catal, 7, 2024
创建时间：
2023-06-13
