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资源简介：
RNA sequencing of Young and Old CD4 & CD8 T-cell subsets.
应用场景：
创建时间：
2021-06-03
相关数据集
Decreased production of IL-23, IL-12p70 and IL-12/23p40 in response to LPS+R848 stimulation in a subgroup of frail old individuals.
Whole blood cells from frail (n = 10) and non frail (n = 9) old individuals were stimulated with LPS+R848 during 24 h. IL-12/23p40, IL-12p70 and IL-23 were measured in cell-free supernatants by ELISA.
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T cell responses to H1N1v and a longitudinal study of seasonal influenza vaccination - 2010
Systems biology approach to examine effects of seasonal flu vaccination in adults of different ages on gene expression, cytokine stimulation and serum cytokines with parameters such as immune senescen
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FcgRIIB+ and FcgRIIB- OT-I T cells d14 post OVA skin graft
Here, we sought to characterize the transcriptomes of FcγRIIB+ versus FcγRIIB- CD8+ T cells in a mouse model of transplant rejection to understand the function of FcγRIIB in programming CD8 T cells re
NIAID Data Ecosystem20
RNA-seq comparison of gene induction in RIG-I stimulated old and young human monocytes. Homo sapiens
Goal: The goal of this study was to compare gene induction in old and young human monocytes upon stimulation of these cells with a RIG-I specific ligand, based on previously published results which in
NIAID Data Ecosystem30
Data_Sheet_1_Defective Transcriptional Programming of Effector CD8 T Cells in Aged Mice Is Cell-Extrinsic and Can Be Corrected by Administration of IL-12 and IL-18.PDF
In response to infection with intracellular microorganisms, old mice mobilize decreased numbers of antigen-specific CD8 T cells with reduced expression of effector molecules and impaired cytolytic act
NIAID Data Ecosystem20
