five

Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors

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Protein Data Bank Japan2024-03-20 更新2026-03-21 收录
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资源简介:
Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors Descriptor: 5-chloro-6-ethyl-2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}pyrimidin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... Authors: Chen, T.T, Chen, T, Xu, Y.C. Deposit date: 2011-06-17 Release date: 2011-08-24 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.449 Å) Cite: Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors. J.Med.Chem., 54, 2011
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2011-06-17
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