Cryo-EM structure of the agonist setmelanotide bound to the active melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein at 2.6 A resolution.
收藏Protein Data Bank Japan2024-11-13 更新2026-04-25 收录
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Cryo-EM structure of the agonist setmelanotide bound to the active melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein at 2.6 A resolution. Descriptor: CALCIUM ION, Camelid antibody fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P. Deposit date: 2021-08-23 Release date: 2021-11-17 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (2.58 Å) Cite: Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide. Cell Res., 31, 2021
创建时间:
2021-08-23



