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Crystal Structure of CDK2 in complex with pan-CDK Inhibitor

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Crystal Structure of CDK2 in complex with pan-CDK Inhibitor Descriptor: 4-((5-BROMO-4-(PROP-2-YN-1-YLAMINO)PYRIMIDIN-2-YL)AMINO)BENZENESULFONAMIDE, CYCLIN-DEPENDENT KINASE 2 Authors: Luecking, U, Jautelat, R, Krueger, M, Brumby, T, Lienau, P, Schaefer, M, Briem, H, Schulze, J, Hillisch, A, Reichel, A, Siemeister, G. Deposit date: 2013-03-26 Release date: 2013-09-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.95 Å) Cite: The Lab Oddity Prevails: Discovery of Pan-Cdk Inhibitor (R)- S-Cyclopropyl-S-(4-{[4-{[(1R,2R)-2-Hydroxy-1-Methylpropyl]Oxy}-5-(Trifluoromethyl)Pyrimidin-2-Yl]Amino}Phenyl)Sulfoximide (Bay 1000394) for the Treatment of Cancer. Chemmedchem, 8, 2013
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2013-03-26
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