Towards Precision Cancer Care: Advancements in Magnetic Particle Imaging and Magnetic Hyperthermia Therapy

Imaging is crucial for detecting tumours and monitoring treatment efficacy. However, current cancer treatments like chemotherapy and radiation therapy often cause severe side effects by damaging both the tumour cells and healthy tissue. In my PhD, I explored Magnetic Particle Imaging, a new imaging system that uses iron oxide nanoparticles as contrast agents. These nanoparticles specifically accumulate at tumours, allowing precise and sensitive detection. When exposed to a magnetic field, the nanoparticles can be heated, raising the tumour's temperature and selectively killing cancer cells. This method offers a more sensitive, specific, and potentially safer alternative for tumour diagnosis and treatment.