Liposome formulation for drug delivery

Given the hydrophobicity of coumarins (OT-55), we used another route of administration by encapsulating our molecule of interest. First generation liposomes are effective because they are close to the composition of biological membranes. A thoughtful choice that made it possible to avoid the phenomena of rejection or hypersensitivity. The proportions for the formulation were studied and showed a saturation phenomenon. To be sure that we had trapped our coumarin synthesis, a panoply of tests were carried out (well detailed in the manuscript), additional data were added in order to characterize our entity. We therefore use ATR-FTIR to demonstrate an interrelation between coumarin and membrane phospholipids.