Data for: Effects of testosterone on gene expression are concordant between sexes but divergent across species of Sceloporus lizards

Hormones mediate sexual dimorphism by regulating sex-specific patterns of gene expression, but it is unclear how much of this regulation involves sex-specific hormone levels versus sex-specific transcriptomic responses to the same hormonal signal. Moreover, transcriptomic responses to hormones can evolve, but the extent to which hormonal pleiotropy in gene regulation is conserved across closely related species is not well understood. We addressed these issues by elevating testosterone levels in juvenile females and males of three Sceloporus lizard species prior to sexual divergence in circulating testosterone, then characterizing transcriptomic responses in the liver. In each species, more genes were responsive to testosterone in males than in females, suggesting that early developmental processes prime sex-specific transcriptomic responses to testosterone later in life. However, overall transcriptomic responses to testosterone were concordant between sexes, with no genes exhibiting sex..., , , # Data for: Effects of testosterone on gene expression are concordant between sexes but divergent across species of Sceloporus lizards

## Overview

[https://doi.org/10.5061/dryad.fj6q57432](https://doi.org/10.5061/dryad.fj6q57432)

README code and data file explanation for: \"Effects of testosterone on gene expression are concordant between sexes but divergent across species of *Sceloporus* lizards\"

Robinson CD, MD Hale, CL Cox, HB John-Alder, and RM Cox. 2024. Effects of testosterone on gene expression are concordant between sexes but divergent across species of *Sceloporus* lizards. The American Naturalist. 

Email addresses and ORCIDs:

CDR*, corresponding author: [[e-mail]](mailto:[e-mail]); 0000-0002-1874-4660

MDH: [[e-mail]](mailto:[e-mail]); 0000-0003-0338-847X

CLC: [[e-mail]](mailto:[e-mail]); 0000-0002-9424-8482

HBJ-A: [[e-mail]](mailto:[e-mail]); 0000-0001-5036-592X

RMC: [rmc3u...