five

NiPPeR Study - pilot microbiome investigation

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NIAID Data Ecosystem2026-03-12 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA707065
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The NiPPeR double-blinded randomized controlled trial recruited 1,729 women prior to conception and followed 585 mother-infant dyads from delivery to examine the impact of a nutritional supplement [containing additional micronutrients, myo-inositol and probiotics - Lactobacillus rhamnosus NCC 4007 (CGMCC 1.3724; LPR) and Bifidobacterium animalis sp. lactis NCC 2818 (CNCM I-3446; Bl818)] taken before and during pregnancy on the health of mothers and their babies. In this pilot study, we analyzed 20 stool samples, collected six months after birth, from 10 mother-infant dyads within the NiPPeR cohort (five from Auckland, New Zealand; five from Southampton, United Kingdom) to characterize vertical mother-to-infant microbial transmission and subsequent adaptation in bacterial transcription.
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2021-03-05
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