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Saccharomyces cerevisiae CYP51 Y140F mutant complexed with posaconazole in the active site

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4ze1
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Saccharomyces cerevisiae CYP51 Y140F mutant complexed with posaconazole in the active site Descriptor: Lanosterol 14-alpha demethylase, POSACONAZOLE, PROTOPORPHYRIN IX CONTAINING FE Authors: Sagatova, A, Keniya, M.V, Wilson, R, Tyndall, J.D.A, Monk, B.C. Deposit date: 2015-04-20 Release date: 2016-03-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase. Sci Rep, 6, 2016
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2015-04-20
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