65 prostate cancer cases WGS and transcriptome sequencing project. Homo sapiens

Prostate cancer is the most frequently diagnosed cancer and the second leading cause of cancer death in the American men, accounting for 238,590 new diagnoses and 29,720 deaths in 2013. Its incidence is also rising worldwide, especially in Asian countries. Prostate tumors exhibit large variable clinical outcomes, with some patients having>10-year survival, but others, particularly those with an aggressive tumor phenotype, only surviving 2–3 years after diagnosis. Here, we obtained whole-genome sequencing and paired transcriptome data of 65 prostate tumors and paired adjacent benign tissues to give more comprehensive analyses of genetic alterations at both the DNA and RNA level from the same patients are warranted.