To investigate the effect of STAT3 knockdown on transcription, we constructed control and STAT3 knockdown HepG2 cell lines by shRNA. We then performed gene expression profiling using data obtained fro
Hepatocellular carcinoma is a poor prognosis cancer leading to death, with high rate of recurrence after curative therapy. The functions of Covalently closed circular RNA (circRNAs) in HCC recurrence
Neuroblastoma (NB) is the most common extra cranial solid tumor in infants. Although several risk factors including patient age, disease stage and genetic abnormalities, such as MYCN amplification and
Tumor-derived cell lines have served as vital models to advance our understanding of oncogene function and therapeutic response1. Although substantial effort has been directed to defining the genomic