Environmentally Friendly Protocol for the Oxidative Iodofunctionalization of Olefins in a Green Solvent

An environmentally
friendly iodofunctionalization of olefins for
the synthesis of various iodinated products was developed via the
oxidative umpolung of iodide using I2O5 as the
inorganic oxidant. The distinct advantages of this protocol over all
previous methods include no generation of organic byproducts and the
use of a green solvent, thus greatly reducing the environmental impact.
Additionally, mild reaction conditions, good yields, and easy-to-operate
features make the current reaction system a more attractive method
for the synthesis of a variety of medicinal and agrochemical compounds
of interest.