Smooth muscle cell Piezo1 depletion results in impaired contractile properties in murine small bowel: Supp Figure Data
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Title: Smooth muscle cell Piezo1 depletion results in impaired contractile properties in murine small bowelLoss of Piezo1 in smooth muscle cells (SMCs) of the small bowel disrupts gut motility by impairing contractility, Ca²⁺ flux, and stretch-induced responses. Specifically, Piezo1-deficient SMCs lead to weight loss, delayed transit, muscularis thinning, altered cellular profiles, and expression of ion channels critical for motility, while also resulting in dysrhythmic Ca2+ signaling in vitro. Supplementary data: Figure graph data values
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2025-01-15
