VX-680/MK-0457 binds to human ABL1 also in inactive DFG conformations.
收藏Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4zog
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VX-680/MK-0457 binds to human ABL1 also in inactive DFG conformations. Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-METHOXYETHANOL, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, ... Authors: Kyomuhendo, P, Narayanan, D, Engh, R.A. Deposit date: 2015-05-06 Release date: 2016-09-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: VX-680/MK-0457 binds also to human ABL1 with inactive DFG conformations. To Be Published
创建时间：
2015-05-06
