High-throughput sequencing of Trastuzumab CDRH3 variant yeast display library

High-throughput sequencing dataset for Trastuzumab CDRH3 variant library.

Each library sample is created from flow cytometry-sorted yeast cells displaying variant Trastuzumab on the cell surface and categorized based on binding affinity with HER2:

Sample 1: Tz variants strong binders

Sample 2: Tz variants intermediate binders

Sample 3: Tz variants weak binders

All processed data and weights from 'Baselining the Buzz. Trastuzumab-HER2 Affinity, and Beyond!' can be found in data.zip