SLC22A2

ENCODES a protein that exhibits choline transmembrane transporter activity (ortholog); organic cation transmembrane transporter activity (ortholog); quaternary ammonium group transmembrane transporter activity (ortholog); INVOLVED IN histamine transport (ortholog); monoatomic cation transport (ortholog); organic cation transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); acute kidney failure (ortholog); end stage renal disease (ortholog); FOUND IN basolateral plasma membrane (ortholog); cholinergic synapse (ortholog); presynaptic membrane (ortholog); INTERACTS WITH cimetidine; penconazole; tebuconazole

编码一种表现出胆碱跨膜转运活性（同源物）的蛋白质；有机阳离子跨膜转运活性（同源物）；季铵基团跨膜转运活性（同源物）；参与组胺转运（同源物）；单原子阳离子转运（同源物）；有机阳离子转运（同源物）；参与阿米洛利药理学通路；贝纳氟噻嗪药理学通路；布美他尼药理学通路；与3-甲基戊二酸尿症伴发耳聋、脑病及Leigh综合征（同源物）；急性肾衰竭（同源物）；终末期肾病（同源物）；存在于基底外侧质膜（同源物）；胆碱能突触（同源物）；突触前膜（同源物）；与西咪替丁、喷康唑、特比萘芬相互作用。