Duodenal inflammation in Common variable immunodeficiency has altered transcriptional response to viruses
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP384324
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资源简介:
To elucidate the role of duodenal microenvironment in Common variable immunodeficiency pathogenesis (CVID), we sought to explore the transcriptome regulation in duodenal biopsies. Overall design: Total RNA was isolated from snap-frozen pieces of duodenal biopsies and analyzed by RNA-seq in CVID, celiac disease and healthy controls. Comparative gene expression profiling between healthy control and disease condition. CVID_N = CVID with normal levels of intraepithelial lymphocytes CVID_IEL = CVID with increased levels of intraepithelial lymphocytes celiac = celiac disease control = healthy control
创建时间:
2022-11-04



