Gene expression data from T47D human breast ductal carcinoma cells treated with prolactin and/or NIM811. Gene expression data from T47D human breast ductal carcinoma cells treated with prolactin and/or NIM811

The hormone prolactin is implicated in the pathogenesis of breast cancer, and a subset of prolactin-induced gene expression is mediated by CypA activity. The non-immunosuppressive prolyl isomerase inhibitor, NIM811, is an inhibitor of CypA. We used NIM811 in combination with prolactin treatment in T47D cells to determine differential expression under these conditions. Overall design: T47D cells were serum starved for 24 hours prior to treatment with NIM811 and/or prolactin, and subsequent RNA extraction.