One-Pot Synthesis of 3,5-Disubstituted and Polysubstituted Phenols from Acyclic Precursors
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下载链接:
https://figshare.com/articles/dataset/One_Pot_Synthesis_of_3_5_Disubstituted_and_Polysubstituted_Phenols_from_Acyclic_Precursors/2189353
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资源简介:
A new
strategy for the synthesis of 3,5-disubstituted phenols is
established through one-pot Robinson annulation of α,β-unsaturated
ketones with α-fluoro-β-ketoesters followed by in situ
dehydrofluorination and tautomerization. This method has been extended
to the synthesis of polysubstituted phenols and applied in the preparation
of biologically active compounds.
创建时间:
2016-02-14



