Stability constants K and half saturation constants Ks for chloroquine and related blocker-substrates to PA-channels, when added to the cis-side of lipid bilayer membranes.
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The data represent means of at least three individual titration experiments. Ks values from chloroquine are given for comparison and were taken from [31]. Membranes were formed from diphytanoyl phosphatidylcholine/n-decane. The aqueous phase contained 150 mM KCl, 10 mM MES, pH 6.0, and about 1 ng/ml PA63; T = 20°C.
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2015-12-02
