VP1 gene point mutations that have occurred in the PV Sabin -derived Slovakian aVDPV2 strains before the study period.
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Included are 33 nt sites where all SVK-aVDPV2 differed from PV2 Sabin, and seven sites where a few strains showed back mutation. This did not always result in reversion at amino acid level because of other coinciding mutations in the codon. Nucleotide transversions are indicated by bold phase. In addition, synonymous transitions were seen in sites 15, 39, 63, 66, 138, 177, 192, 213, 228, 258, 276, 288, 291, 364, 399, 405, 465, 477, 504, 516, 522, 543, 594, 606, 615, 654, 675, 690, 756, 789, 828, 885, 897.
创建时间:
2013-06-28



