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Immunotherapy study of phagocytosis checkpoint blockade in combination with radiotherapy

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE197767
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Transcriptional profiling of tumor-infiltrating antigen-presenting myeloid subsets and CD8 T cells in mice bearing MC38-OVA tumors treated with or without radiotherapy, αSIRPα, and/or αPD-1 treatment CD11b-CD11c+, CD11b+CD11c+, and CD11b+CD11c- myeloid populations and CD8 T cells were isolated from the irradiated tumors 5 days after 8-Gy or sham irradiation +/- αSIRPα and αPD-1 for RNA-sequencing analyses.
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2022-07-21
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