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RNA-seq of mouse brain tissue investigating the effect of absence of microglia in the developing brain

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https://www.ncbi.nlm.nih.gov/sra/ERP160953
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Microglia, brain-resident macrophages, have been proposed to play an active role in synaptic refinement and maturation, influencing plasticity and circuit-level connectivity. Using a genetically modified mouse which lacks microglia (Csf1r ?FIRE/?FIRE), we investigate the effect on gene expression of the presence or absence of microglia in the developing mouse brain.
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2024-08-23
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