Transcriptomic analysis of Saccharopolyspora hirsuta VKM Ac-666

NIAID Data Ecosystem2026-03-13 收录

放线菌转录组

胆固醇代谢调控

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https://www.ncbi.nlm.nih.gov/sra/SRP387814 数据链接链接失效反馈

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资源简介：

The aim of this work was to investigate the transcriptomic response of the moderately thermophilic actinobacteria Saccharopolyspora hirsuta VKM Ac-666 to cholesterol.

创建时间：

2022-08-06

Transcriptional changes of selected components of the cholesterol and bile acid biosyntheses.

胆固醇代谢调控

基因表达谱分析

RNA sequencing was performed with RNA from livers of 10 animals of each genotype. Means of the expression ratio (KO/WT) for each gene are listed. For p-value calculations an unpaired two-tailed Studen

NIAID Data Ecosystem40

Quantitative Analysis of erythroblast cells Transcriptomes treated with cholesterol or not. Quantitative Analysis of erythroblast cells Transcriptomes treated with cholesterol or not

血细胞终末分化

胆固醇代谢调控

In our work, we explored the dynamics of cholesterol homeostasis during terminal erythropoiesis. Interestingly, we found differential requirements of cholesterol during terminal erythropoiesis, with t

NIAID Data Ecosystem30

Table_1_Taxonomic Description and Genome Sequence of Christensenella intestinihominis sp. nov., a Novel Cholesterol-Lowering Bacterium Isolated From Human Gut.DOCX

肠道微生物分类鉴定

胆固醇代谢调控

A Gram-staining-negative, non-spore-forming, short, straight rod, non-motile, and obligate anaerobic bacterial strain, AF73-05CM02T, was isolated from a fecal sample of a 30 years old healthy male liv

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Clustering of the altered genes in response to TLR1/2 or TLR4 activation in SZ95 sebocytes.

细胞免疫反应

胆固醇代谢调控

Genes that were regulated both by PAM3CSK4 and LPS were functionally categorized using the Cytoscape classification system. The clusters clearly defined an immunocompetence for the activated sebocytes

Figshare2018-06-21 更新30

Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis

胆固醇代谢调控

正向遗传筛选

Somatic cell genetics is a powerful approach for unraveling the regulatory mechanism of cholesterol metabolism. However, it is difficult to identify the mutant gene(s) due to cells are usually mutagen

NIAID Data Ecosystem30

Transcriptomic analysis of Saccharopolyspora hirsuta VKM Ac-666

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