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Inhibition of IL6 signalling as a therapeutic strategy to eradicate cancer cells with chromosomal instability

ChEBI2022-04-13 更新2026-07-12 收录

癌症靶向治疗

IL6信号通路抑制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-10923 数据链接链接失效反馈

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Inhibition of IL6 signalling as a therapeutic strategy to eradicate cancer cells with chromosomal instability

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创建时间：

2022-04-13

癌症靶向治疗

甲基转移酶抑制剂

Small molecule binding data for protein Histone-arginine methyltransferase CARM1, Protein arginine N-methyltransferase 1, and Protein arginine N-methyltransferase 5, Uniprot O14744, Q86X55, and Q99873

DataCite Commons2024-04-26 更新30

The therapeutic effect of KSP inhibitors in preclinical models of cholangiocarcinoma

癌症靶向治疗

KSP抑制剂机制

Cholangiocarcinoma (CCA) is an epithelial malignancy with a dismal prognosis owing to limited treatment options. Here, we identified several compound candidates against CCA using a high-throughput dru

NIAID Data Ecosystem20

Additional file 5 of Interpreting drug synergy in breast cancer with deep learning using target-protein inhibition profiles

药物协同预测

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Supplementary Material 5.

Figshare2024-08-18 更新10

Internal stimuli-responsive nanocarriers for controlled anti-cancer drug release: a review

纳米药物递送

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Table S1: Nanostructured biomolecules approved or in clinical trials for cancer therapy [8]. Table S2: examples of pH-responsive medication delivery systems. Table S3. Nanocarriers

DataCite Commons2024-05-17 更新30

Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system

癌细胞重编程

癌症靶向治疗

Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

NIAID Data Ecosystem10

Inhibition of IL6 signalling as a therapeutic strategy to eradicate cancer cells with chromosomal instability

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