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In vivo prime editing in the liver using AAV vectors and lipid nanoparticle-mediated mRNA delivery

NIAID Data Ecosystem2026-03-14 收录

基因编辑技术

器官靶向基因治疗

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA947564 数据链接链接失效反馈

官方服务：

资源简介：

Improvement of in vivo prime editing in adult mouse livers

应用场景：

创建时间：

2023-03-22

脑肿瘤研究

基因编辑技术

Diffuse intrinsic pontine gliomas (DIPGs) are highly lethal childhood brain tumors. Their unique genetic makeup, pathological heterogeneity, and brainstem location all present challenges to treatment.

干细胞与再生医学数据中心2022-02-20 更新110

Chromosomal Manipulation by Site-Specific Recombinases and Fluorescent Protein-Based Vectors

基因编辑技术

疾病模型构建

Feasibility of chromosomal manipulation in mammalian cells was first reported 15 years ago. Although this technique is useful for precise understanding of gene regulation in the chromosomal context, a

NIAID Data Ecosystem70

gene editing in rice by CRISPR/Cpf1

基因编辑技术

遗传改良

To demonstrate Cpf1 can be engineered to modify PAM recognition, broadening the targeting range in rice.

NIAID Data Ecosystem30

prime editing 20230226

基因编辑技术

先导编辑实验

prime editing

NIAID Data Ecosystem70

Role of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: Cut&Tag. Role of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: Cut&Tag

白血病机制研究

基因编辑技术

Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutati

NIAID Data Ecosystem60

In vivo prime editing in the liver using AAV vectors and lipid nanoparticle-mediated mRNA delivery

资源简介：

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