Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (2R)-IKM-159 at 2.3A resolution.
收藏Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (2R)-IKM-159 at 2.3A resolution. Descriptor: (4aS,5aR,6R,8aS,8bS)-5a-(carboxymethyl)-8-oxo-2,4a,5a,6,7,8,8a,8b-octahydro-1H-pyrrolo[3',4':4,5]furo[3,2-b]pyridine-6-carboxylic acid, CHLORIDE ION, Glutamate receptor 2, ... Authors: Juknaite, L, Frydenvang, K, Kastrup, J.S. Deposit date: 2013-01-17 Release date: 2013-03-20 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization. J.Med.Chem., 56, 2013
创建时间：
2013-01-17
