five

PXR activation in 3T3L1 and NIH3T3 fibroblasts

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These data demonstrate the effects of pregnenolone 16a-carbonitrile, a pregnane x receptor agonist, in two murine fibroblast models on fibroblast function including in vitro scratch wound healing, cellular migration, proliferation, myofibroblast differentiation, and extracellular matrix production. There data are in support of a recently submitted manuscript.
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2026-03-23
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