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Langerhans dendritic cell differentiation and TGFbeta

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE31318
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To identify genes with a potential role in Langerhans dendritic cell differentiation, progenitor cells from human cord blood were analyzed by Affymetrix GeneChip U133Plus 2.0 microarray profiling Human CD34+CD45Rahi hematopoietic progenitor cells were cultured for 2 days in GM-CSF, FLT3L, SCF and TNFa before TGFbeta was added or not. RNA was analyzed at 0h, 6h and 24h relative to addition of TGFbeta. Total RNA from 6 independent donors was isolated and combined into two separate pools (A and B), each containing RNA from 3 different donors.
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2019-03-25
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