RNAseq transcriptomic data of healthy primary human mammary epithelial cells from WT, BRCA1 mutated or BRCA2 mutated patients

Normal primary epithelial cells from women following reduction mammoplasty or BRCA1 or 2 mutated women following preventive mastectomy were purified from the mammary tissue and analyzed by RNAseq. Since all samples were certified tumor-free by an anatomo-pathologist prior to processing, this study aims to better understand the transcriptomic alterations inudced by BRCA genes mutations in primary cells prior to any detectable transformation event. Overall design: mRNA profiles of WT, BRCA1 mutated and BRCA2 mutated human primary mammary epithelial cells (3 independent samples for each genotype)