Folate deficiency in vascular smooth muscle cells. Folate deficiency in vascular smooth muscle cells

Folate deficiency promotes differentiation of vascular smooth muscle cells, but shifts the overall phenotype towards skeletal muscle Overall design: A7r5 rat vascular smooth muscle cells were grown in medium containing 100ng/ml (excess), 10ng/ml (sufficient) or 2.5ng/ml of folic acid (deficient) for 7, 14 and 21 days