The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway.

ChEBI2011-11-23 更新2026-07-21 收录

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细胞稳健性

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-33844 数据链接链接失效反馈

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The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway.

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2011-11-23

Effect of neuron-specific spliced XBP1 (XBP1s) overexpression on gene expression in the mouse brain. Effect of neuron-specific spliced XBP1 (XBP1s) overexpression on gene expression in the mouse brain

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脑缺血/中风神经保护

One major component of cellular proteome resides in the endoplasmic reticulum (ER), the key organelle for protein biogenesis in the secretory pathway. Disruption of ER proteostasis leads to ER stress,

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Genes with ATF5 binding sites within their promoters from Uncovering a mitochondrial unfolded protein response in corals and its role in adapting to a changing world

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The Anthropocene will be characterized by increased environmental disturbances, leading to the survival of stress-tolerant organisms particularly in the oceans where novel marine diseases and elevated

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The effect of ER-stress and subsequent activation of the unfolded protein response was investigated in colon cancer stem cells and more differentiated colon cancer cells Human colon cancer derived sph

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Additional file 5: of Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans

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Raw data of Phsp-6::GFP reporter measurements. Gene-by-gene data of the fold change (FC) and adjusted P value (adj.pvalue) obtained after data analysis. RNAi clones appear ordered by their position in

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The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway.

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内质网稳态

Stress pathways monitor intracellular systems and deploy a range of regulatory mechanisms in response to stress. One of the best-characterized pathways, the unfolded protein response (UPR), is respons

NIAID Data Ecosystem30

The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway.

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