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Cell fusion-mediated pluripotent reprogramming triggers ordered changes in chromatin and gene expression across the human inactive X chromosome

ChEBI2016-07-01 更新2026-07-12 收录

X染色体失活

表观遗传重编程

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-77443 数据链接链接失效反馈

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Cell fusion-mediated pluripotent reprogramming triggers ordered changes in chromatin and gene expression across the human inactive X chromosome

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创建时间：

2016-07-01

单细胞RNA测序

X染色体失活

The primers used and the validation of candidate escape genes. (XLSX 11 kb)

DataCite Commons2024-12-16 更新100

HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [RNA-seq]. HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [RNA-seq]

红细胞生成低氧应答

表观遗传重编程

We performed RNA-sequencing on erythropoietic cells cultured in normoxia or hypoxia at days 3,7, and 10. We found numerous expression changes induced by hypoxia, including the canonical hypoxia target

NIAID Data Ecosystem40

Jpx RNA controls Xist induction through spatial reorganization of the mouse X-inactivation center, Oh et al.

X染色体失活

非编码RNA功能

Known to regulate chromosome looping on a genome-wide scale, the noncoding Jpx RNA was originally shown to control X-chromosome counting and induce Xist expression during X-chromosome inactivation (XC

NIAID Data Ecosystem10

Xist Repeats A and B account for two distinct phases of X-inactivation establishment. Xist Repeats A and B account for two distinct phases of X-inactivation establishment

X染色体失活

表观遗传调控

X-chromosome inactivation (XCI) is a global silencing mechanism by which XX and XY mammals equalize X-linked gene dosages. XCI begins with an establishment phase during which Xist RNA spreads and indu

NIAID Data Ecosystem40

H3K27me3 and CTCF ChIP-seq in reciprocal wild-type and SmcHD1 MommeD1mut MEF cell lines. H3K27me3 and CTCF ChIP-seq in reciprocal wild-type and SmcHD1 MommeD1mut MEF cell lines

表观遗传调控

X染色体失活

In this study we investigate the role of the non-canonical SMC family protein, SmcHD1in the X inactivation. Overall design: Set of allele-specific ChIP-seq experiments on female clonal inter-specific

NIAID Data Ecosystem30

Cell fusion-mediated pluripotent reprogramming triggers ordered changes in chromatin and gene expression across the human inactive X chromosome

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