Bovine genome assembly by Cattle Genome Sequencing International Consortium

The Cattle Genome Sequencing International Consortium, led by the Baylor College of Medicine, originally sequenced the Bos taurus genome at 6x coverage using a whole genome shotgun (WGS) strategy. The initial assembly (Btau_4.2) was later replaced by newer versions by incorporating high quality finished data, where available (Btau_4.6.1). The latest version takes the UMD 3.1 assembly contigs and scaffolds and incorporates ~19x Pacific Biosciences long-read data using the PBJelly method (English, Richards et al. 2012).

由贝勒医学院领导的国际牛基因组测序联盟，最初采用全基因组鸟枪法（WGS）对牛（Bos taurus）基因组进行了6倍覆盖度的测序。初始组装版本（Btau_4.2）随后被通过整合高质量完成数据的新版本所取代，当可获得时（Btau_4.6.1）。最新版本采用了UMD 3.1组装的连续片段和支架，并利用PBJelly方法（Richards et al., 2012）融合了约19倍覆盖度的太平洋生物科学长读长数据。