RNA-seq analysis of Scx-lineage cell depletion to investigate tendon cell functions during flexor tendon healing
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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资源简介：
Little is understood about the roles of tendon cells during flexor tendon healing. To better understand tendon cell functions, the Scx-Cre mouse was crossed to the DTR mouse model to facilitate scleraxis lineage cell depletion prior to acute flexor tendon injury and repair. WT (cre-) and experimental (cre+) mice underwent complete transection and repair of the flexor digitorum longus tendon. Repaired tendons were harvested at 14 and 28 days post-repair for bulk RNA-Seq analysis to examine possible mechanisms driving differential healing due to Scx lineage cell depletion.
提供机构：
University of Rochester
创建时间：
2022-02-20
