Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors
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Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors Descriptor: (3R,5R)-7-{2-[(4-fluorobenzyl)carbamoyl]-4-(4-fluorophenyl)-1-(1-methylethyl)-1H-imidazol-5-yl}-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase Authors: Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. Deposit date: 2008-02-26 Release date: 2008-06-17 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
创建时间：
2008-02-26
