BCR-Seq of Germinal Center B cells from mice infected with LCMV
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https://www.ncbi.nlm.nih.gov/sra/SRP342409
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资源简介:
To study how acute or chronic viral infection (LCMV-WE or Docile) affect somatic hypermutation and/or affinity maturation of Germinal Center B cells, wild-type or Bmi1-deleted mice were infected with either the acute (WE) versus chronic (Docile) strains of LCMV, GC B cells (CD19+IgDloCD95+CD38loCD138-) were isolated 14 days post-infection and thei BCR was sequenced. Overall design: 8 samples. Each group has at least 2 biological replicates.
创建时间:
2022-01-20



