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Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI12

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI12 Descriptor: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, N-[(benzyloxy)carbonyl]-L-valyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-methylidene-L-norvalinamide Authors: Yang, K.S, Liu, W.R. Deposit date: 2022-04-28 Release date: 2023-01-25 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.63 Å) Cite: A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease. Acs Chem.Biol., 18, 2023
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2022-04-28
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