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Low dose irradiation enhances gene targeting in human pluripotent stem cells

ChEBI2016-03-22 更新2026-07-12 收录

干细胞基因编辑

辐照增强基因靶向

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-68328 数据链接链接失效反馈

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资源简介：

Low dose irradiation enhances gene targeting in human pluripotent stem cells

应用场景：

创建时间：

2016-03-22

男性健康研究

干细胞基因编辑

Azoospermia patients who carry a monogenetic mutation that causes meiotic arrest may have their biological child through genetic correction in spermatogonial stem cells (SSCs). However, such therapy f

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whole genome sequencing of TAM-edited iPSCs

干细胞基因编辑

全基因组脱靶检测

To determine the off-target mutagenesis of TAM in iPSCs

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Unraveling MLL1-fusion Leukemia: Epigenetic Revelations from an iPS Cell Point Mutation

白血病表观遗传学

干细胞基因编辑

Human iPS cells (WT ASE9203 cells) were obtained from Applied Stem Cell (ASC), and CRISPR-Cas9-mediated gene editing was completed by ASC using their proprietary CRISPR-Cas9 protocol to introduce the

NIAID Data Ecosystem60

SNP analysis of human induced pluripotent stem cells. Homo sapiens

干细胞基因编辑

基因组稳定性分析

Human induced pluripotent stem cells (hIPSCs) represent a unique opportunity for regenerative medicine since they offer the prospect of generating unlimited quantities of cells for autologous transpla

NIAID Data Ecosystem70

Generation of targeted homozygosity in the genome of human induced pluripotent stem cells

干细胞基因编辑

移植配型

When loss of heterozygosity (LOH) is correlated with loss or gain of disease phenotype, it is often necessary to identify which gene or genes are involved. Here, we generated a region-specific LOH-ind

NIAID Data Ecosystem60

Low dose irradiation enhances gene targeting in human pluripotent stem cells

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