five

RNA sequencing of control and dnm2-knockout mouse sciatic nerves

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE113106
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In this study, we analyzed the transcriptome profiles of mouse sciatic nerves after developmental (P1 and P5) or inducible (4 weeks post Tamoxifen) deletion of Dnm2 conditionally in Schwann cells (using a P0Cre-driven or a P0CreERT2-driven recombination of floxed alleles, respectively) as compared to controls (floxed Dnm2 homozygous, Cre-negative). mRNA profiles from controls and mutants were collected in triplicate from developmental sciatic nerves at P1 and P5, as well as from inducible mice at 4 weeks post tamoxifen
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2019-03-21
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