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Processed mosaic of a sagittal section through the brain of mouse model of glioma. To produce transformed cells, creGFAP mice were injected in the cortex with Ras/s.i.p53 virus and perfused after 8 weeks. In this system, GFP is introduced by the virus and expression is induced by an IRES site in the mRNA. Thus, the GFP gene is expressed whenever the virus infects a cell expressing GFAP (green). The section was immunolabeled for nestin (red) and counterstained with DAPI (blue). See MP:8011 for a section from the same brain labeled with GFAP.经处理的鼠模型胶质瘤大脑矢状切面镶嵌图像。为生成转化细胞，通过向皮质注射Ras/s.i.p53病毒并经8周后灌注，对creGFAP小鼠进行处理。在该系统中，病毒引入GFP蛋白，其表达由mRNA中的IRES位点诱导。因此，每当病毒感染表达GFAP（绿色）的细胞时，GFP基因即被表达。切片经巢蛋白（红色）免疫染色，并用DAPI（蓝色）进行复染。欲了解更多信息，请参阅MP:8011中标记有GFAP的同一脑部切片。