Synthesis of Calothrixins and Its Analogs Using FeCl3‑Mediated Domino Reaction Protocol
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A novel one pot synthesis of calothrixin B and its analogs is achieved involving an FeCl3-mediated domino reaction of enamines in dry DMF at reflux. Alternatively, the enamines upon interaction with CuBr2 in DMF at reflux led to the formation of 1-phenylsulfony-2-(2′-nitroaryl)-4-hydroxycarbazole-3-carbaldehydes in excellent yields.
创建时间:
2016-02-19



