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Transcriptional regulation in the embryonic endocardium after NOTCH pathway manipulation. Transcriptional regulation in the embryonic endocardium after NOTCH pathway manipulation

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NIAID Data Ecosystem2026-03-14 收录
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We have manipulated the NOTCH signaling pathway in mouse embryonic endocardial cells by the co-culture with OP9 stromal cells expressing Jag1 and Dll4, the culture over recombinant JAG1 and DLL4, and the use of the γ-secretase inhibitor RO4929097. We have performed RNA-seq and ATAC-seq to define the transcriptional profile and the chromatin accessibility landscape specific for each condition. Overall design: Refer to individual Series

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2023-01-25
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